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乳胶 I 型过敏目前尚无有效的治疗方法。虽然换用非乳胶手套能够大幅减少不良反应、降低敏化风险，但很多医护人员在换用后出现了化学品 IV 类过敏。了解乳胶和化学品过敏的不同原因和症状，对医院制定相关决策非常重要。
通常而言，过敏是指人体对外来物质（称为‘过敏原’）的敏感度增加，造成人体防御系统（免疫系统）过度反应。在正常情况下，免疫系统只在有害物质（如细菌）攻击人体时做出反应。而过敏人群的免疫系统过于“警惕”，即使是相对无害的物质（如手套中的化学品）也可能招致攻击。过敏造成的后果程度不一，既可能只是轻微不适，也可能危及生命（如过敏反应）。
对过敏原的反应可能表现为刺激或敏化。
参考文献
1. Geier J, Lessmann H, Mahler V, Pohrt U, Uter W and Schnuch A. Occupational contact allergy caused by rubber gloves – nothing has changed. Contact Dermatitis, 67, 149–156
2. Cao L., Taylor J, Sood A, Murray D, Siegel P. Allergic Contact Dermatitis to Synthetic Rubber Gloves. Changing Trends in Patch Test Reactions to Accelerators. Arch Dermatol, Vol. 146 (NO.9), 2010.
3. Ponten A, Hamnerius N, Bruze M, Hansson C, Persson C, Svedman C, Andersson K and Bergendorff O. Occupational allergic contact dermatitis caused by sterile non-latex protective gloves: clinical investigation and chemical analyses. Contact Dermatitis, 68, 103-110
4. Kiellen MB. 2010. Handeksem av latexfria handskar (Hand eczema from latex-free gloves). Uppdukat. 2:30-31.
5. Rose RF, Lyons P, Horne H, Wilkinson SM. 2009. A review of the materials and allergens in protective gloves. Contact Dermatitis. 61:129-137.
6. Compared to Ansell's general thickness neoprene gloves.
7 - 12. References available upon request
