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Dynamic Chemotherapy Drug Permeation Testing

Ansell’s Cytostatic Permeation Program (ACPP) is a unique dynamic permeation test designed to give healthcare professionals working with hazardous drugs a perspective of how working conditions may influence the permeation of your glove’s protective barrier. ACPP gives you an added confidence advantage as current ASTM1 and EN2 standards testing are static and do not reflect the impact glove properties such as thickness; the stretching and flexing motion of the task, as well as both body and workplace temperatures will have on permeation of chemo tested gloves. 3,4,5,6

What’s the difference between ASTM & EN standards testing and ACPP?

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FOR SAFER HANDLING OF CHEMO DRUGS, LET ACPP ALSO BE YOUR GUIDE

ASTM and EN chemotherapy standards testing are often mandatory and must always be available as your guide. ACPP testing gives you an in-use perspective to make the right glove choice for safer handling of chemotherapy drugs. Unlike standards, ACPP mimics everyday use in the workplace through controlled dynamic conditions. 

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WORKING CONDITIONS ARE DYNAMIC, SO WHY NOT TEST TO IN-USE CONDITIONS?

THE ADVANTAGE OF DYNAMIC PERMEATION TESTING

Minimizing your risk of exposure to hazardous drugs starts by using all available permeation data. Having both Standards and ACPP permeation results available is an advantage to help you choose the right glove.

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HOW ACPP WORKS

Ansell is the only glove manufacturer with its own dynamic permeation testing method and device. Watch ACPP in action.

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CHOOSING THE RIGHT GLOVE: ACPP & ASTM/EN TESTED

1. ASTM or American Society for Testing Materials refers to ASTM D6978. 2. EN or European Norm refers to EN 16523-1. 3. Nalin M, Hug G, Boeckmans E, Machon C, Favier B and Guitton J. Permeation measurement of 27 chemotherapy drugs after simulated dynamic testing on 15 surgical and examination gloves: A knowledge update. Journal of Oncology Pharmacy Practice. 2020;0(0):1-14. 4. Landeck L, Gonzalez E, Koch OM. Handling chemotherapy drugs-Do medical gloves really protect?. Int J Cancer. 2015;137(8):1800-1805. doi:10.1002/ijc.29058. 5. Phalen RN, Le T, Wong WK. Changes in chemical permeation of disposable latex, nitrile, and vinyl gloves exposed to simulated movement. J Occup Environ Hyg. 2014;11(11):716-721. doi:10.1080/15459624.2014.908259. 6. Dillon J and Schroeder L. Permeability and material characteristics of vulcanized latex film during and following cyclic fatigue in a saline environment. Journal of Applied Polymer Science. 1997;64(3):553-566.